Natural Ingredients For Natural Pain Relief

Read about our Ingredients, Implemented Based on Fact and Research

Our Doctors used the most natural pain fighting ingredients they could find to help aid in natural pain relief.

“I think supplements can be the cornerstone of good pain management,” writes David C. Leopold, MD, director of Integrative Medical Education at the Scripps Center for Integrative Medicine in a WebMD article.

Natural supplements promise many of the benefits of traditional medicines with fewer side effects and risks.
At Holistic Pain, we use a variety of natural ingredients in our bone and cartilage, head, nerve, and spine formulas. More information is provided below about each of these ingredients in our formulas.

Boswellia Serrata

Boswellia serrata is also known as Indian frankincense. It has been used for centuries to treat inflammation in the practice of Asian Ayurvedic medicine. It is believed that boswellia serrata’s inflammatory effects are due to four different acids in the substance. Recent studies have linked these effects to benefits for rheumatoid and osteoarthritis sufferers, as well as irritable bowel conditions.


A placebo-controlled study from the journal Neurology found that nearly 70% of patients who took butterbur supplements noted a greater than 50% reduction in their migraine symptoms. Butterbur is a natural herb that has been used extensively to treat head pain. It is likely that butterbur helps head pain by preventing swelling and pressure on the head’s blood vessels.

Coenzyme Q10

Coenzyme Q10 (or CoQ10) is a component of our body’s cellular structure that is most notably found in the heart, liver, and kidneys. A deficiency in CoQ10 can cause fatigue and weakness in the body. CoQ10 supplements have been used to help patients with muscular dystrophy, Lyme disease, and chronic fatigue syndrome.

Devil’s Claw

An African herb with a mighty punch, devil’s claw has long been used in herbal remedies for muscle pain and inflammation. Studies show that devil’s claw may have benefits for knee and hip pain related to osteoarthritis, as well as other causes of joint pain.

Fish Oil

In a WebMD article, David P. Rakel, the founder and director of the University of Wisconsin’s Integrative Medicine Program, notes that “fish oil is the clean-up hitter of supplements.” It may help ease inflammation and pain caused by multiple chronic pain conditions. Omega-3s, the fatty acid in fish oil, can help with headaches, back pain, and rheumatoid arthritis. They can also help alleviate fatigue.

Folic Acid

Folic acid is most well-known for its role in preventing birth defects. However, this powerful supplement is also recommended by the American Nutrition Association to improve hearth health and lower heart attack risk.

Ginseng Root And Ginkgo Biloba

Ginseng root and ginkgo biloba are modern-day supplements with ancient stories. These herbs can complement many traditional treatment plans. Gingko biloba improves blood circulation and may help remove free radicals from the blood stream. Ginseng root, on the other hand, has long been used to help the body relax and improve recovery times.

Glucosamine And Chondroitin

Glucosamine is a naturally occurring compound in the body that helps the body build cartilage. When taken with chondroitin, it shows promise for helping with several pain conditions. With pain conditions like osteoarthritis, the degradation of cartilage over time can lead to pain. The National Institutes of Health rates glucosamine as likely effective for treating osteoarthritis pain—of the knee, hip, and spine. David C. Leopold, director of Integrative Medical Education at the Scripps Center for Integrative Medicine, notes in a WebMD article, “When it comes to joint pain, I think glucosamine supplements have some of the best data out there.” The article goes on to note, “There’s especially strong evidence that this pain supplement can help relieve osteoarthritis pain in the knee. Glucosamine is often combined with chondroitin, which could have an additional benefit.”


What makes your body decide that it’s time to sleep? It turns out that a special hormone called melatonin is largely responsible for this process. Melatonin, a hormone produced in the pineal gland, gauges the amount of light and in that way helps regulate our circadian rhythms.

Modern life, with its artificial light sources, can sometimes trick the body during its production of melatonin. This can cause sleep problems that then leads to pain complications or mental health concerns. By isolating melatonin and using it as a supplement, however, it may be possible to reset the body’s internal clock. Recent research has shown that taking melatonin can help night shift workers sleep during the day and travelers adjust to new time zones.

S-Adenosyl Methionine (SAMe)

S-adenosyl methionine (SAMe) is a naturally occurring substance in the body, however, no foods that we eat contain this substance. Some studies have suggested that taking it in supplement form can improve certain health conditions, including osteoarthritis and depression. One study from the Journal of Family Practice notes that SAMe has the possibility to treat pain in patients with osteoarthritis, especially in reducing functional limitation.

St. John’s Wort

St. John’s Wort is an herb that has been used medicinally since the time of ancient Greece. According to the Mayo Clinic, there is strong scientific evidence for the use of St. John’s Wort for mild to moderate depression and good evidence for its use for somatoform mental disorders.

Willow Bark

Willow bark from specific varieties of the willow tree may prove useful for treating inflammation and pain. A 200 person study in the American Journal of Medicine tested willow bark’s effects on low back pain. Those who received high doses of the supplements had a significant decrease in back pain, with researchers noting that willow bark extract was a “useful and safe treatment for low back pain.”


We are just beginning to scientifically understand many of the benefits that herbal supplements can provide. Whether found in our bodies already, or in the trees or plants, supplements promise new treatment options for many pain conditions. As a WebMD article notes, “Natural pain relief and traditional medicine don’t have to stand in opposition.” At Holistic Pain, we believe that there are healthful, natural options that can be used in combination with traditional medical options.